TO STUDY THE EFFECTIVENESS OF HOMOEOPATHIC MEDICINES IN ‘LM’ POTENCY IN CASES OF OSTEOARTHRITIS

Authors

  • Dr. Arkajyoti Sardar M.D.(Hom.) (Scholar), Department of MateriaMedica, Sri Ganganagar Homoeopathic Medical College Hospital & Research Institute, Tantia University, Sriganganagar (Raj.)
  • Dr. Vinay Kumar M.D.(Hom.), Ph.D.(Hom.) Professor, Department of Materia Medica, Sri Ganganagar Homoeopathic Medical College Hospital & Research Institute, Tantia University, Sriganganagar (Raj.)

DOI:

https://doi.org/10.53555/1x7sav10

Keywords:

Osteoarthritis, Homoeopathy, LM Potency, 50 MillesimalScale, WOMAC, Individualized Medicine, Clinical Trial

Abstract

Background- Osteoarthritis (OA) is a chronic, degenerative disorder of synovial joints that increasingly affects the aging population, leading to pain, stiffness, restricted mobility, and disability. Conventional therapies often offer only symptomatic relief and may produce long-term adverse effects. Homoeopathic LM (50 millesimal) potencies, as introduced in the Sixth Edition of the Organon of Medicine, are known for their gentle, deep, and individualized therapeutic action with minimal aggravations. However, scientific literature regarding their effectiveness in OA remains limited, necessitating clinical evaluation.

Aim- To study the effectiveness of individualized Homoeopathic medicines in LM potency in cases of Osteoarthritis. Methodology-An open-label, prospective clinical study was conducted on 100 cases of osteoarthritis aged 40 years and above, attending the OPD/IPD of Sri Ganganagar Homoeopathic Medical College Hospital & Research Institute. Patients were selected based on inclusion and exclusion criteria, and written informed consent was obtained. Individualized remedies in LM potencies were prescribed after detailed case taking, repertorization, and MateriaMedica confirmation. WOMAC (Western Ontario & McMaster Universities Osteoarthritis Index) was used to assess pain, stiffness, and physical function before and after treatment. Data were statistically analyzed using paired t-test via SPSS software (ver.16).

Results- Highly significant improvement was observed in all components of the WOMAC score. The mean difference between pre- and post-treatment scores was 4.57, with a standard deviation of 4.367. The calculated t-value was 10.481, with p < 0.001, indicating strong statistical significance and rejecting the null hypothesis. Commonly indicated medicines included Rhustoxicodendron, Ruta, and Bryonia, corresponding to the dominant miasmatic patterns (Psora and Sycosis).

Conclusion- Individualized Homoeopathic medicines in LM potency demonstrated significant therapeutic benefits in cases of osteoarthritis, reducing pain, stiffness, and functional disability as reflected in improved WOMAC scores. The findings support the clinical usefulness and safety of LM potencies as an effective complementary approach for osteoarthritis management. 

References

1. Harrisons principles of internal medicine. New York: Mcgraw-Hill, Cop; 2012

2. Vinay Kumar, Abul K Abbas, John C Aster. Robbins Basic Pathology. 9th ed. Vol. 1. Canada: Elesvier; 2019. 1 vols.

3. Panel GP Dobson et. al.Defining the osteoarthritis patient: back to the future. Osteoarthritis and Cartilage. Volume 26, Issue 8, August 2018, Pages 1003-1007.

4. Abramoff B, Caldera FE. Osteoarthritis. Medical Clinics of North America. 2020 Mar; 104(2):293–311. doi:10.1016/j.mcna.2019.10.007.

5. Dennis McGonagle, Ai Lyn Tan et. al. The anatomical basis for a novel classification of osteoarthritis and allied disorders. Journal of Anatomy. 2010 Jan 7; 216(3):279–291. doi: 10.1111/j.1469-7580.2009.01186.x

6. Dopson GP. Defining the osteoarthritis patient: back to the future. Osteoarthritis and Cartilage.Volume 26, Issue 8, August 2018, Pages 1003-1007

7. Springer BD. Management of the Bariatric Patient. What Are the Implications of Obesity and Total Joint Arthroplasty: The Orthopedic Surgeon's Perspective? J Arthroplasty. 2019 Jul;34(7S):S30-S32. [PubMed]

8. Elsiwy Y, Jovanovic I, Doma K, Hazratwala K, Letson H. Risk factors associated with cardiac complication after total joint arthroplasty of the hip and knee: a systematic review. J OrthopSurg Res. 2019 Jan 11;14(1):15. [PMC free article] [PubMed]

9. Lundgren-Nilsson Å, Dencker A, Palstam A, Person G, Horton MC, Escorpizo R, Küçükdeveci AA, Kutlay S, Elhan AH, Stucki G, Tennant A, Conaghan PG. Patient-reported outcome measures in osteoarthritis: a systematic search and review of their use and psychometric properties. RMD Open. 2018;4(2):e000715. [PMC free article] [PubMed]

10. Manlapaz DG, Sole G, Jayakaran P, Chapple CM. Risk Factors for Falls in Adults with Knee Osteoarthritis: A Systematic Review. PM R. 2019 Jul;11(7):745-757. [PubMed]

11. GBD 2019: Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. https://vizhub.healthdata.org/gbd-results/.

12. Kisand K, Tamm AE, Lintrop M, Tamm AO. New insights into the natural course of knee osteoarthritis: early regulation of cytokines and growth factors, with emphasis on sex-dependent angiogenesis and tissue remodeling. A pilot study. Osteoarthritis Cartilage. 2018 Aug;26(8):1045-1054. [PubMed]

13. Collins NJ, Hart HF, Mills KAG. Osteoarthritis year in review 2018: rehabilitation and outcomes. Osteoarthritis Cartilage. 2019 Mar;27(3):378-391. [PubMed]

14. Afzali T, Fangel MV, Vestergaard AS, Rathleff MS, Ehlers LH, Jensen MB. Cost-effectiveness of treatments for non-osteoarthritic knee pain conditions: A systematic review. PLoS One. 2018;13(12):e0209240. [PMC free article] [PubMed]

15. Alrushud AS, Rushton AB, Bhogal G, Pressdee F, Greig CA. Effect of a combined programme of dietary restriction and physical activity on the physical function and body composition of obese middle-aged and older adults with knee OA (DRPA): protocol for a feasibility study. BMJ Open. 2018 Dec 14;8(12):e021051. [PMC free article] [PubMed]

16. Long H, Liu Q, Yin H, Diao N, Zhang Y, Lin J et al. Prevalence trends of site-specific osteoarthritis from 1990 to 2019: Findings from the global burden of disease study 2019. Arthritis Rheumatol 2022; 74(7): 1172-1183.

17. Cieza A, Causey K, Kamenow K, Wulf Hansen S, Chatterji S, Vos T. Global estimates of the need for rehabilitation based on the Global Burden of Disease study 2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020 Dec 19; 396(10267): 2006–2017.

18. Mahajan A, Verma S, Tandon V; Update Article; journal of association of physician of India •VOL. 53 • JULY 2005;www.japi.org p;636-41.

19. Majoosi A I, KamilusSanah. (Urdu translation by Kantoori GH) New Delhi: IdaraKitabusShifa. 2010; 543-46.

20. Razi Z. Kitab al-Hawi. Vol 11th. Central Council for Research in Unani Medicine, New Delhi,2004; 75.

21. orreia W, Reis JH, Pires E Albuquerque RS, de Paula Mozela A, de Souza EB, Maia PV, Barretto JM. Outcomes after knee arthroplasty in extra-articular deformity. IntOrthop. 2019 Sep;43(9):2065-2070. [PubMed]

22. Tashjian RZ, Chalmers PN. Future Frontiers in Shoulder Arthroplasty and the Management of Shoulder Osteoarthritis. Clin Sports Med. 2018 Oct;37(4):609-630. [PubMed]

23. Motiwala, F.F.: Kundu, Tapas; Bagmar, Kamlesh; Kakatkar, Vijay: Dhole, Yogesh:. Effect of Homoeopathic Treatment on Activity of Daily Living (ADL)in Knee Osteoarthritis: A Prospective Observational Study, Indian Journal of Research in Homoeopathy, ISSN number- 0974-7168, E-ISSN number 2320- 7094, Volume number-10. Issue number-3, July-September 2016, Published by CentralCouncilforResearchin Homoeopathy, NewDelhi, India, Pagenumber - 182 to 187.

24. Rajgurav, Atul B.; Aphale, Parth To Study the Efficacy of Rhustox in Management of Cases of Osteoarthritis of Knee Joint,International Journal of Research in Orthopaedics, ISSN number 2455-4510. January-February 2017, Volume number-3, Issue number-1. Published by Medlip Academy, Page number-54 to 60.

25. Singh,Kumar,Atul,Dr.;Bhindra,Ashok,Dr.,Meena,Ajay,Dr.;The Efficacy of Homoeopathic Medicines in Management of Osteoarthritis with the help of Repertories, Advancements In Homoeopathic Research, ISSN number - 2456-3688,Volumenumber-3,Issuenumber-1,February2018-April2018, Published by HFY Enterprises, New Delhi-110002, Page number-30 to 43.

26. Bhattacharyya S, ChatterjeeC, Saha S, NaskarS, Bhattacharya P, AlamSM, Sengupta S, Ahamed S, Shaikh AR, Koley M, Ghosh P, Mukherjee SK. Individualized Homeopathic Medicinesin the Treatment ofKnee Osteoarthritis: Double-Blind, Randomized, Placebo-Controlled Feasibility Trial.PubMed, Homeopathy.2023Sep25.doi:10.1055/s-0043-1771025.ISSNNo.1475-4916, PMID:37748512.

27. Kumar N, Iyer N. An observational study on the effect of individualised homoeopathic medicine administered based on totality of symptoms vis-à-vis personality in cases of osteoarthritis knee. Indian J Res Homoeopathy, ISSN number-0974-7168,E-ISSNnumber2320-7094,Volume15,IssueNO2(2021), 2021;15(2):103-112.doi:10.4103/ijrh.ijrh_86_19.

28. L De Schepper. LM potencies: one of the hidden treasures of the sixth edition of the Organon. Br Homeopath J 1999; 88(03): 128-134 DOI: 10.1054/homp.1999.0309

29. U. C. Adler, A. T. Cesar, M. S. Adler, A. Alves, E. N. Garozzo, W. M. P. Galhardi , A. E. Padula, I. C. Souza. LM or Q Potencies- Review of Their Use Over a Fifteen-Year Period. Homœopathic Links 2005 (Posology); 18(2): 87-91. DOI: 10.1055/s-2005-837714.

30. Patel RP. My experiments with 50 millesimal scale potencies: 5th Edition. Hahnemann Homoeopathic Pharmacy: Dr. Ramanlal P. Patel; 1998.

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Published

2025-10-18

How to Cite

TO STUDY THE EFFECTIVENESS OF HOMOEOPATHIC MEDICINES IN ‘LM’ POTENCY IN CASES OF OSTEOARTHRITIS. (2025). EPH-International Journal of Applied Science, 11(2), 122-129. https://doi.org/10.53555/1x7sav10