MEDICINAL PLANT: GLYCYRRHIZA GLABRA AND ITS EFFICACY IN IN VITRO AGAINST FASCIOLA GIGANTICA LARVA
DOI:
https://doi.org/10.53555/42gsbh61Keywords:
Glycyrrhiza glabra, Fascioliasis, Sporocyst, Redia, CercariaAbstract
Fascioliasis is an economically important disease, which caused by Fasciola (liver fluke) among cattle and human. Class trematoda has Fasciola hepatica and F. gigantica which are worldwide. The intermediate host of Fasciola is Lymnaeidae snail. Fasciola is a hermaphrodite and their larval stages (sporocyst, redia and cercaria) are completed within the host snail. Infection of this disease can be control by destroy the larval stages. The aim of this study is to use of different preparation of Glycyrrhiza glabra plant in in vitro against sporocyst, redia and cercaria larva of F. gigantica. Each experimental setup of Petri dish contains 10 larvae. The dried root powder, organic extracts and column purified fractions were exposed in 10 ml dechlorinated water against sporocyst, redia and cercaria within 2h, 4h, 6h and 8h separately. The column purified fraction were shows after 2h LC50 51.15, 48.42 and 55.69 mg/ml and 8h LC50 45.95, 40.15, and 45.62 mg/ml efficacy against sporocyst, redia and cercaria, respectively.
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