ABNORMALITIES OF TESTICULAR FUNCTION OF MALE WISTAR RATS FED SOME PROTEIN SUPPLEMENTS

Authors

  • Osama M. Y. El-barasi Zoology Department. Arts and Science Faculty. Omar Al Mukhtar University, Derna, Libya
  • Yousef M. AL-kelany Zoology Department. Arts and Science Faculty. Omar Al Mukhtar University, Derna, Libya

DOI:

https://doi.org/10.53555/eijas.v1i3.10

Keywords:

Protein supplements, blood picture, T3&T4, biochemistry, histopathology

Abstract

Athletes and bodybuilder consumed high protein supplements to obtain a lot of energy and enhance the development and strength of their muscles. However, after time, different investigations revealed dysfunctions of their body organs. There are contradictions between scientists concerning the benefits and the alarm of developing body dysfunction. In the present work, we selected three animal groups of male Wistar albino rats (n=10), control, hyper whey (HW) 2.6g/kg body weight and super amino 2500 (SA) 2.6g/kg body weight. The dose was provided through a healthy water tap for 14 weeks. The body weight was regularly measured. At the end of experiment, animals were sacrificed, dissected and blood collected from puncture of heart and the testes were removed and weighed. A biochemical analysis of function testes and histopathological investigations are done. From Morphometrical prospect, the total number of seminiferous tubules were markedly decreased in HW & SA. On the other hand, by using histopathological method on the symbol supplemented by WH, the spermatogenic cells were apparently declined and lacked normal pattern of arrangement. There was a noticeable increased number of necrotic spermatocytes and cell debris occupied the central region of the tubular lumina. Super amino supplementation revealed alterations of the seminiferous tubules. There was a clear reduction of spermatogenic cells. Biochemically. In HW and SA supplemented groups, it has registered a decrease in plasma total testosterone. The levels of T3 and T4 was markedly decreased in HW supplementation and slightly affected in SA fed rats

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Published

2015-09-27