EFFECT OF HONEY AND OLIVE OIL ON SERUM CHOLESTEROL LEVELS: A PRELIMINARY STUDY

Authors

  • Alemam H Biotechnology Research Center (BTRC), Tripoli, Libya
  • Abugeela M Department of Biochemistry, Faculty of Pharmacy, University of Tripoli (Tripoli-Libya).
  • Lamami Y Biotechnology Research Center (BTRC), Tripoli, Libya
  • Enattah N Biotechnology Research Center (BTRC), Tripoli, Libya
  • Bashein A Department of Biochemistry, Faculty of Medicine, University of Tripoli (Tripoli-Libya). Biotechnology Research Center

DOI:

https://doi.org/10.53555/eijas.v7i2.63

Keywords:

Olive oil, Honey, total cholesterol, fatty acids, gas chromatography

Abstract

Cholesterol is probably the best known steroid because of its association with atherosclerosis. Previous studies shown association of olive oil use with reduced serum cholesterol levels. In addition, honey has been shown to have beneficial effects on lipid profiles. Therefore, this study was carried out to investigate the effects of olive oil and honey on total cholesterol level in healthy Libyan individuals. The study was conducted on 75 Libya volunteers aged 40-55 years divided into 3 groups including, 25 olive oil group aged 49.47±2.15, honey group aged 50.07±2.01, olive oil and honey group aged 52.07±4.31. The total cholesterol level was measured before and after the experiment and expressed as (mg/dL).The chemical and physical properties of the olive oil used in the study were found to be compatible with permitted limits issued by the Libyan National Centre of Standardization and Metrology .Our results showed that olive oil and honey significantly reduced total serum cholesterol (p<0.001) and (p<0.05) respectively. Furthermore, combination of olive oil and honey significantly reduced total cholesterol (p<0.001) by 21%. We conclude that the utilization of olive oil and honey can lead to a significant decrease in the levels of total serum cholesterol in blood.

References

. Zárate A, Manuel-Apolinar L, Basurto L, De la Chesnaye E, Saldívar I. Cholesterol and atherosclerosis. Historical considerations and treatment. Arch Cardiol Mex. 2016 Apr-Jun;86(2):163-9

. Rondanelli M, Giacosa A, Morazzoni P, Guido D, Grassi M, Morandi G, Bologna C, Riva A, Allegrini P, Perna S. MediterrAsian Diet Products That Could Raise HDL-Cholesterol: A Systematic Review. Biomed Res Int. 2016;2016:2025687

. Khalil MI, Tanvir EM, Afroz R, Sulaiman SA, Gan SH. Cardioprotective Effects of Tualang Honey: Amelioration of Cholesterol and Cardiac Enzymes Levels. Biomed Res Int. 2015;2015:286051.

. Owen RW, Giacosa A, Hull WE, Haubner R, Würtele G, Spiegelhalder B, et al. Olive-oil consumption and health: the possible role of antioxidants. Lancet Oncol. 2000; 1:107–12.

. Escrich E, Moral R, Solanas M. Olive oil, an essential component of the Mediterranean diet, and breast cancer. Public Health Nutr. 2011;14:2323–32

. Lewis, V., Hoeger, K. Prevention of coronary heart disease: a nonhormonal approach. Semin. Reprod. Med. 2005;23:157–166

. Libyan standard specifications, no. 8 of 1983 issued by national center of specification and standard criteria (2007).

. Krichevsky D. Sallata, D. Tepper. S.A. Effect of olive oil on (Altherosclerosis and cancer) Res-8,697. F. from (2003).

. Katsilambros NL, Philippides P, Touliatou A, Georgakopoulos K, Kofotzouli L, Frangaki D, et al. Metabolic effects of honey (alone or combined with other foods) in type II diabetics. Acta Diabetologica Latina 2004;25(3):197–203

. Yaghoobi N, Al-Waili N, Ghayour-Mobarhan M, Parizadeh SM, Abasalti Z, Yaghoobi Z, et al. Natural honey and cardiovascular risk factors; Effects on Blood Glucose, Cholesterol, Triacylglycerole, CRP and Body weight Compared with Sucrose. ScientificWorldJournal 2008;8:463–9.

. Al-Waili N, Parizadeh SM, Abasalti Z Natural honey and cardiovascular risk factors; Effects on Blood Glucose, Cholesterol, Triacylglycerole, CRP and Body weight Compared with Sucrose. Scientific World Journal 2004; 8:463–9.

. Kandil A, El-Banby M; Abdel-Wahed K, Abou-Sehly G, Ezzat N (1987) Healing effect of true floral and false nonfloral honey on medical wounds. J Drug Res (Cairo) 17(1–2): 71–5

. Zumla A, Lulata: composition of honey (honey-aremedy) J. royak Soc. Medicine. (2002), 82:3844-386.

. Zambon A, Sartore G, Passera D, Francini-Pesenti F, Bassi A, Basso C, Zambon S, Manzato E, Crepaldi G. Effects of hypocaloric dietary treatment enriched in oleic acid on LDL and HDL subclass distribution in mildly obese women. J Intern Med. 1999 Aug; 246(2):191-201.

. Carrasco-Pancorbo A, Cerretani L, Bendini A, Segura-Carretero A, GallinaToschi T, Fernandez-Gutiérrez A. Analytical determination of polyphenols in olive oils. J Sep Sci. 2005 Jun;28(9-10):837-58.

. Libyan standard specifications, no. 8 of 1983 issued by national center of specification and standard criteria (2007).

. Escrich E, Moral R, Solanas M. Olive oil, an essential component of the Mediterranean diet, and breast cancer. Public Health Nutr. 2011;14:2323–32

. Al-Nozha MM, Ismail HM, Al Nozha OM. Coronary artery disease and diabetes mellitus. Journal of Taibah University Medical Sciences (2016) 11(4), 330e338.

. Zhang ZF, Kim IH. Effects of dietary olive oil on egg quality, serum cholesterol characteristics, and yolk fatty acid concentrations in laying hens. J Appl Anim Res. 2014;42:233–7.

. Kris-Etherton PM, Pearson TA, Wan Y, Hargrove RL, Moriarty K, Fishell V, Etherton TD. High-monounsaturated fatty acid diets lower both plasmas cholesterol and tria-cylglycerol concentrations Am Cline Nutr 70(6).1009-15, 1999. Am J Clin Nutr. 1999 Dec;70(6):1009-15

. Hu FB, Manson JE, Willett WC. Types of dietary fat and risk of coronary heart disease: a critical review. J Am Coll Nutr. 2001 Feb;20(1):5-19

. Visioli F, Galli C. Olive oil: more than just oleic acid. Am J Clin Nutr. 2000 Sep;72(3):853.

. Al-Waili NS. Natural honey lowers plasma glucose, C-reactive protein, homocysteine, and blood lipids in healthy, diabetic, and hyperlipidemic subjects: comparison with dextrose and sucrose. J Med Food 2004;7:100–7.

. Kas'ianenko VI, Komisarenko IA, Dubtsova EA. Correction of atherogenic dyslipidemia with honey, pollen and bee bread in patients with different body mass. Ter Arkh. 2011;83(8):58-62

. Münstedt K, Hoffmann S, Hauenschild A, Bülte M, von Georgi R, Hackethal A. Effect of honey on serum cholesterol and lipid values. J Med Food. 2009 Jun;12(3):624-8.

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Published

2021-06-27

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Vol. 7 No. 2 (2021): EPH - International Journal of Applied Science ( ISSN: 2208-2182 )

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